Benjamin Netanyahu has been indicted on charges of bribery, fraud and breach of trust, becoming the first sitting Israeli PM to face criminal charges.
The decision comes hours after Mr Netanyahu abandoned his bid for immunity.
Israel's Attorney General Avichai Mandelblit's office filed the indictment with Jerusalem District Court on Tuesday.
The case has loomed over the prime minister for months and plagued him during both Knesset elections last year. Israelis are to return to the polls on March 2 for the third time in a year, after negotiations failed to produce a workable coalition.