Born into a Jewish family in Michigan, Blair attended Hillel Day School, a Jewish day school in Farmington Hills. She has appeared in films including Cruel Intentions (1999), Legally Blonde (2001) and The Sweetest Thing (2002). She will appear in the Netflix series Another Life later this year.
She has said that she was inspired to speak candidly about her condition because of costume designer Allisa Swanson.
“[S]he carefully gets my legs in my pants, pulls my tops over my head, buttons my coats and offers her shoulder to steady myself. I have #multiplesclerosis,” she wrote.
Blair also spoke of the support she had received from her producers:
“By the grace of the lord, and will power and the understanding producers at Netflix , I have a job. A wonderful job.”