On January 24, he will travel to Bethlehem, where he will meet Palestinian President Mahmoud Abbas.
In a statement, a Clarence House spokesperson said that the engagements in Israel were “focused on his deep interest in Jewish faith and culture and on the vibrancy of the UK – Israel relationship.”
The Prince has previously visited Israel twice – in 1995 for the funeral of Prime Minister Yitzhak Rabin and in 2016 for the funeral of President Shimon Peres – both times in a private capacity.
It follows Prince William's visit in June last year, the first ever official visit by a senior Royal.
Charles' wife, the Duchess of Cornwall, will visit Auschwitz on Holocaust Memorial Day, where around 200 Holocaust survivors will take part in events commemorating the 75th anniversary of the camp’s liberation in 1945.