Inbal Pezaro recovered from a slow start to give Israel its first medal of the 2012 London Paralympics.
The five-time Paralympic medallist added a bronze to her collection after a miraculous comeback in the 50m freestyle final.
Pezaro had finished runner-up in her heat at the Aquatics Centre.
Other Day One highlights saw Yoav Valinsky finish sixth in the Men's 100m Backstroke.