“The stabbing victim was treated at the scene for a stab wound in his upper body, following which he was transported to the hospital for further care while fully conscious,” Dov Maisel, United Hatzalah paramedic who was among the first at the scene, told the Jerusalem Post.
CCTV footage of the incident showed the suspects, holding knives, approaching the group of officers and suddenly attacking one policeman.
The other officers then pulled out their guns and shot the suspects several times.
Gates to the Temple Mount were temporarily closed following the incident.
This incident comes after clashes at Temple Mount on Sunday as the Muslim festival of Eid al-Adha coincided with the Jewish fast day of Tisha B’Av.
Israeli security forces scuffled with Palestinians at the holy site — known to Muslims as Haram esh-Sharif — after protesters had gathered amid rumours that Jewish visitors would be permitted entry.