Player recruitment hit Prestfield hard in their second season as they struggled to field teams this term.
The loss of star striker Jonny Franks also had a big affect on the league's bottom club.
League chairman Paul Rose said: “We are sorry to see Prestfield go.
“To lose any team, at any stage, is disappointing. But I’m glad the situation hasn't dragged out where their results have major implications on the league.
“I’ve known they have struggled to field teams for a while. Zac has been very honest about the situation and try as he might the numbers were not there every week.
“Sadly it was a battle they just couldn't win.”
