Avram Grant is the 6/4 favourite to replace Tony Adams as manager of Portsmouth.
Adams was sacked on Sunday night, following the 3-2 defeat against Liverpool.
A Portsmouth spokesman said: "The priority is for Portsmouth football club to remain in the top flight and we feel the appointment of a new manager will give us the best opportunity to enable us to do this."
Grant, 53, has been out of work since leaving Chelsea on May 24, just three days after the team lost the Champions League final against Manchester United on penalties. He also helped Chelsea finish runners-up in the League and Carling Cup.