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Sephardim talk testing

November 24, 2016 12:01

By

Daniel Sugarman,

Daniel Sugarman

1 min read

Although we have focused on genetic disorders affecting Ashkenazism, there are other genetic conditions which are far more common among Sephardim. These include Familial Mediterranean Fever, Metachromatic Leukodystrophy, and Spinal Muscular Atrophy Type 1A.

In July, Dor Yesh-orim, the Charedi community's genetic screening programme, introduced testing for a range of diseases more likely to affect Sephardi Jews (some diseases thought of as solely affecting Ashkenazim, like Cystic Fibrosis, can also affect Sephardim).

With Sephardim, the likelihood of being a carrier for a specific genetic disease can depend on country or area of origin.

Familial Mediterranean Fever, for example, is more common among Jews in Iran, Iraq and Mediterranean countries. Metachromatic Leukodystrophy is much more likely to affect Yemenite Habbani Jews. Spinal Muscular Atrophy Type 1A occurs most often among Jews from Egypt.

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