Inbal Pezaro missed out on a third medal at the 2012 Paralympic Games, but Israel's men are assured of a medal in the Quad Singles Wheelchair Tennis competition after excelling in the last eight.
Inbal Pezaro finished fourth in the Women's 100m Breaststroke final after coming home in a time of 1:56:53. She was edged out of what would have been her third bronze of the Games by Teresa Perales of Spain.
Earlier in the day, Pezaro had finished runner-up in her heat at the Aquatics Centre in a time of 1:57:95.
Swimming in Lane 2, Pezaro finished more than 13 seconds behind heat winner Nataliia Prologaieva of Russia who went on to win the final, setting a new world record in the process..
Pezaro has already won medals in the 50m Freestyle and 100m Freestyle.
A time of 39:02 was not enough to earn Inbal Ganapol Shwartz a place in the final of the 50m Freestyle S6.
Erel Halevi finished sixth in her heat of the Women's 50m Freestyle S7 in a time of 38:30.
Israel is guaranteed a medal in the Men's Quad Singles Wheelchair Tennis competition after Shraga Weinberg and Noam Gershony reach the semi-final stage following excellent performances in their respective last eight matches at Eton Manor.
Weinberg came from a set down to beat defending champion Peter Norfolk of Great Britain 3-6, 7-5, 6-0 after a two-hour 16-minute marathon.
He said: "I expected a very tough match. I'm very, very happy. I couldn't be happier to defeat him in front of his home crowd."
Norfolk commented: "I thought Shraga played okay. The big change was in my grip and not hitting it back in court. If you don't hit it in the court you can't win."
Second seed Gershony eased past Bryan Barten of America 6-1, 6-1 in just 45 minutes.
Weinberg will play Gershony for a place in the gold medal match on Thursday afternoon.
Boaz Kramer failed to make the last four after going down David Wagner 6-3, 6-0 in just over an hour.
There was more disappointment for Yonatan Dressler who finished last in the Individual Freestyle Test - Grade III at Greenwich Park. He completed the course in 60:250.
Hagar Zehavi and Shimon Ben Yakov placed eighth out of 11 in the Two-Person Keelboat (SKUD18) in Weymouth.
Dror Shazari claimed a final score of 691.8 to finish a respectable sixth in the final of the Mixed R6-50m Rifle Prone-SH1 at the Royal Artillery Barracks.