A UK-based anti-Israel website with the web address shoah.org.uk has been described as "sickening" and "abhorrent".
The website, called Shoah: The Palestinian Holocaust, refers to "Israhell" and uses terms such as "Zio=Nazi racists".
The site is registered to web designers Creative Spring, which gives its address as the Custard Factory, an arts and media centre in Birmingham.
Creative Spring bought the domain name from an American web hosting company.
A post on the Shoah website, entitled Happy New Year from Shoah, is signed by Sammi Ibrahem Sr, who describes himself as chair.
Someone with the same name chaired a West Midlands Palestine Solidarity Campaign meeting in Sepember about the Gaza flotilla, and has posted several anti-Israel comments on other forums.
Karen Pollock, chief executive of the Holocaust Educational Trust, said: "Using the word 'Shoah' in this context is done with the sole intention of causing offence to Holocaust survivors, their families and the wider Jewish community and shows the greatest possible disrespect to the tragedy of the Holocaust."
Mark Gardner, of the Community Security Trust, said: "This website is yet another sickening example of how the Holocaust is perverted by anti-Zionists in order to attack Israel and Zionism."
Jon Benjamin, chief executive of the Board of Deputies, said: "Even without delving into what is clearly a one-sided and skewed narrative, by virtue of its title, this website is extremely provocative and any trivialisation of the Holocaust in which over six million Jewish men, women, and children were systematically murdered is completely abhorrent."
Neither Mr Ibrahem nor a spokesman for the Custard Factory were available to comment.